Continued from Part 1:
FOR THE PURPOSE OF THIS ARTICLE, IF YOU ARE NOT FAMILIAR WITH THE TERMS USED, PLEASE USE THIS GLOSSARY OF DEFINITIONS LINK TO HELP YOU BETTER UNDERSTAND. WE WILL DO OUR BEST TO BREAK THIS DOWN INTO LAY TERMS SO THE AVERAGE PERSON CAN UNDERSTAND COMPLEX HUMAN PHYSIOLOGICAL PATHWAYS.
THIS IS HOW YOUR BODY WORKS. CHEMICAL REACTIONS HAPPEN INSIDE YOUR BODY BILLIONS UPON BILLIONS OF TIMES SIMULTANEOUSLY EACH DAY. THESE NUTRIENTS ARE THE CHEMICAL COFACTORS, ENZYMES, REAGENTS, ETC. OF THESE CHEMICAL REACTIONS, ALL OF WHICH ARE NECESSARY FOR LIFE’S EXISTENCE, VITALITY, AND HEALTH.
IT IS NOT A MATTER OF WHETHER OR NOT YOU “WANT” TO TAKE THESE NUTRIENTS IN, YOU SIMPLY MUST IN ORDER TO SURVIVE.
FAILURE TO DO SO WILL RESULT IN VARIOUS FORMS OF DISEASE THAT CAN AND WILL PROGRESS TO DEATH.
Vitamin C (water soluble)
Names- Ascorbic Acid, Ascorbate, Ascorbyl
Essential- unlike most animals, are unable to synthesize vitamin C endogenously, so it is an essential dietary component
Sources:
raw coriander/cilantro (more vitamin c compared to the next 3 herbs combined)
raw thyme, parsley, and dill (2x more vitamin c than peppers)
rose hips
all peppers raw (2-5x more vitamin c compared to citrus fruits)
black currants raw
raw tart cherries and acerola cherries
raw citrus fruits
raw saffron, basil, cloves, paprika, black pepper, chili
all raw fruits (things that have a “shell”/skin, flesh inside, and seeds at its core)
grass-fed animal organ meats
grass-fed meat
Functions:
the primary water-soluble, non-enzymatic antioxidant in plasma and tissues. Even in small amounts, vitamin C can protect indispensable molecules in the body, such as proteins, lipids (fats), carbohydrates, and nucleic acids (DNA and RNA), from damage by free radicals and reactive oxygen species (ROS) that are generated during normal metabolism, by active immune cells, and through exposure to toxins and pollutants.
regenerate vitamin E from its oxidized form
synthesis of collagen, carnitine, and neuropeptides, and in the regulation of gene expression
collagen is used in nervous, immune, bone, cartilage, blood, and other cells/tissues.
involved in protein metabolism
influence the methylation status of DNA and histones in mammalian cells by safeguarding genome integrity (protects your DNA)
stimulate both the production and function of leukocytes (white blood cells), especially neutrophils, lymphocytes, and phagocytes.
increase cellular motility, chemotaxis, and phagocytosis (engulf and digest invading microorganisms and foreign particles)
in response to invading microorganisms, phagocytic leukocytes release non-specific toxins, such as superoxide radicals, hypochlorous acid ("bleach"), and peroxynitrite; these reactive oxygen species kill pathogens and, in the process, can damage the leukocytes themselves
through internal storage it protects neutrophils, mononuclear phagocytes, and lymphocytes cell types from oxidative damage
increases interferon production (anti-viral)
enhances the chemotactic and microbial killing capacities of neutrophils and stimulates the proliferation and differentiation of B- and T-lymphocytes
increases the bioavailability of iron from foods by enhancing intestinal absorption of non-heme iron
neutralizes heavy metals, halogens, oxidative free radicals, toxins, and other harmful metabolic waste products
Deficient disease processes- seen in people with poor diets. Vitamin C can be used quickly in those with high oxidative stress from intake of high amounts of toxins. It is also seen in malabsorption disease processes of the GI tract and liver.
potentially fatal disease, scurvy
subcutaneous bleeding, poor wound closure, and bruising easily, hair and tooth loss, and all kinds of arthritic joint pain and swelling, including gout and “autoimmune” arthritic conditions
tissue weakness, failure, and disease
fatigue may result from diminished levels of carnitine, which is needed to derive energy from fat, or from decreased synthesis of the neurotransmitter/hormone norepinephrine
bleeding gums and loosening or loss of teeth due to tissue and capillary fragility
vascular disease processes
iron deficiency anemia
suppressed immune function
cardiovascular disease
viral, bacterial, fungal, and parasitic infections
heavy metal toxicity
halogen toxicity
Dosing
FDA recommended: originally recommended 60 mg per day, but has increased to 90 mg per day
Actual nutritional dose: 500 mg - 2,000 mg daily
Daily therapeutic doses: 2,000 mg - 10,000 mg (10 g) daily
Toxicity: There is no scientific evidence that large amounts of vitamin C (up to 10 grams [g]/day in adults) exert any adverse or toxic effects. High doses should be avoided in those with kidney disease and hereditary conditions like hemochromatosis and glucose 6-phosphate dehydrogenase deficiency.
FAT SOLUBLE VITAMINS
(stored for later use in fat cells and in the liver)
Vitamin A
Names: (preformed Vitamin A) retinol, retinal, and retinoic acid (found in animal meats and milk)
Beta-carotene, alpha-carotene, and beta-cryptoxanthin are pro Vitamin A precursors (found in fruits and vegetables). These must be converted into retinol/retinal/retinoic acid inside the body after digestion.
Essential: meaning you must consume it through your diet
Sources:
grass-fed liver and its oil (beef liver oil) (retinol) has by far the greatest supply of retinol at
wild caught fish and its oil (cod oil) (retinol)
grass-fed milk (retinol)
eggs (retinol)
orange root vegetables like carrots and sweet potatoes (provitamin A carotenoids)
orange fruits like cantaloupe, mango, squash, and pumpkin (provitamin A carotenoids)
Functions:
regulates the expression of over 500 retinoid-responsive genes
significantly involved in immune function
retinoic acid is produced by immune cells on the skin and mucosal cells, lining the airways, digestive tract, and urinary tract, and function as a barrier to form the body's first line of defense against infection.
prevent the development of “autoimmunity” otherwise known as “adaptive immunity”
cellular communication
growth and development, and male and female reproduction
cell growth and differentiation in fetal development, and child/adult maintenance, of the heart, lungs, eyes, and other visceral organs
critical for vision as an essential component of rhodopsin, the light-sensitive protein in the retina that responds to light entering the eye
supports the normal differentiation and functioning of the conjunctival membranes and cornea
significantly reduce carcinogenesis (cancer) in skin, breast, liver, colon, and prostate
Deficient disease processes- seen in people with poor diets. Vitamin A can be used quickly in those with high oxidative stress from intake of high amounts of toxins. It is also seen in malabsorption disease processes of the GI tract and liver.(excess is stored in liver for later use)
acute and chronic infections caused by, and can contribute to, decrease serum and plasma retinol concentrations
increased susceptibility to infections, as well as to thyroid and skin disorders.
changes in the conjunctiva (corner of the eye), manifested by the presence of Bitot's spots
xerophthalmia (Greek for dry eye)
corneal ulcers, scarring, and blindness
decreased immune function
susceptibility to ALL infectious diseases and pathogens
in combination with iodine deficiency results in thyroid dysfunction/disease
Phrynoderma or follicular hyperkeratosis (tiny red bumps on arms/body) (picture)
affects iron mobilization, impairs hemoglobin synthesis, and precipitates iron deficiency anemia
increased risk of cancers
associated with abnormal lung development, respiratory diseases (such as pneumonia), and an increased risk of anemia and death
Dosing: retinol is different than carotenoids. Pay attention to the differences here.
to convert from IUs to mcg or mg, or the other direction, see this link.
For Vitamin A: IUs multiplied by 0.3 gives mcg dose. Mcg’s divided by 0.3 gives IUs.
Retinol activity equivalents (RAE) Ratios for Preformed Vitamin A (retinol) and Provitamin A Carotenoids
Quantity Consumed vs Quantity Bioconverted to Retinol
1 mcg of dietary or supplemental vitamin A gives 1 mcg of retinol* 1:1
2 mcg of supplemental beta-carotene gives 1 mcg of retinol 2:1
12 mcg of dietary beta-carotene gives 1 mcg of retinol 12:1
24 mcg of dietary beta-carotene gives 1 mcg of retinol 24:1
24 mcg of dietary beta-cryptoxanthin gives 1 mcg of retinol 24:1
FDA recommended: 5,000 IUs (1,500 mcg) originally, changed to 3,000 IUs (900 mcg)
Actual nutritional dose: 3,334 IU (1,000 mcg) - 6,667 IU (2,000) mcg per day
Daily therapeutic doses: 4000 IU (1,200 mcg) - 10,000 IU (3,000 mcg) per day
Toxicity: Because vitamin A (retinol) is fat soluble, the body stores excess amounts, primarily in the liver, and these levels can accumulate—especially in people with all types of hepatitis, cirrhosis, all types of fatty liver disease, or large amounts of intrahepatic biliary stones (more on how to correct these dis-ease issues in subsequent articles).
Acute vitamin A toxicity, also referred to as hypervitaminosis A, occurs within days to weeks after someone ingests one or a few very high doses (typically more than 100 times the RDA of retinol).
Resulting signs and symptoms typically include severe headache, blurred vision, nausea, dizziness, aching muscles, and coordination problems. In severe cases, cerebral spinal fluid pressure can increase, leading to drowsiness and, eventually, coma and even death.
Chronic hypervitaminosis A (regular consumption of high doses) can cause
dry skin, painful muscles and joints, fatigue, depression, and abnormal liver test results
Unlike preformed vitamin A (retinol), carotenoids from food are not known to be teratogenic or lead to reproductive toxicity. The most common effect of long-term, excess beta-carotene is carotenodermia, a harmless condition in which the skin becomes yellow-orange. This condition can be reversed by discontinuing beta-carotene ingestion.
Generally, signs of toxicity are associated with long-term consumption of vitamin A in excess of 10 times the RDA (8,000-10,000 μg RAE/day or 25,000-33,000 IU/day), less so with a few very high doses in excess of 100 times the RDA (80,000-100,000 μg RAE/day or 250,000-330,000 IU/day).
Vitamin D
Vitamin D obtained from sun exposure, foods, and supplements is biologically inert and must undergo two hydroxylations in the body for activation. The first hydroxylation, which occurs in the liver, converts vitamin D to 25-hydroxycholecalciferol [25(OH)D], also known as “calcidiol.” The second hydroxylation occurs primarily in the kidney and forms the physiologically active 1,25-dihydroxycholecalciferol [1,25(OH)2D], also known as “calcitriol”
Figure 1 obtained here
Names: calciferol, cholecalfierol, calcidiol, calcitriol
Essential- means you must consume it through sunlight or foods
Sources—SUNLIGHT
Solar ultraviolet-B radiation (UVB; wavelengths of 290 to 315 nanometers) stimulates the production of vitamin D3 in the epidermis of the skin
algae/seaweed eating wild caught fish
the above fish “liver oils”
grass-fed animal “liver oils”
certain mushrooms exposed to UVB rays
Functions
In the presence of 1α,25-dihydroxcholecalciferol, the VDR/RXR complex binds small sequences of DNA known as vitamin D response elements (VDREs) and initiates a cascade of molecular interactions that modulate the transcription of specific genes. Thousands of VDREs have been identified throughout the genome, and VDR activation by 1α,25-dihydroxyvitamin D is thought to directly and/or indirectly regulate 100 to 1,250 genes.
with the parathyroid glands, it is essential for maintenance of bone mineralization through the regulation of calcium and phosphorus homeostasis.
essential for normal bone development and maintenance
essential for maintaining serum phosphorous in a narrow range for normal functioning of the skeletal system
essential for maintaining serum calcium in a narrow range for normal functioning of the nervous system
inhibits proliferation, stimulates the differentiation of cells, and regulating cellular apoptosis (programmed cell death) through binding to the VDR thus preventing and killing cancer.
activate regulatory T cells and antigen-presenting cells, such as dendritic cells and macrophages
activate immune cells like monocytes, macrophages, and T cells to regulate the immune response, enhance innate immunity, and down regulate adaptive immunity (autoimmunity) (restore normal health and immune responses)
Deficient disease processes- When vitamin D3 in skin is inadequate due to insufficient exposure to UVB radiation (preventable with 30 minutes of direct sunlight on more than half of your skin per day minimum—do NOT fall into DARKNESS), oral intake of vitamin D is necessary to meet vitamin D requirements. Use of sunscreen reduces Vitamin D production/intake by more than 90%. Also, malabsorption disease processes of the GI tract and liver result in deficiencies.
Secondary hyperparathyroidism due to vitamin D insufficiency (along with lack of boron) can increase bone breakdown and precipitate osteoporosis.
increased risk of developing dysregulated adaptive immune responses
Osteomalacia (bone softening like osteopenia and osteoporosis)
The geographic distribution of cancer mortality resembles the historical geographic distribution of rickets, providing circumstantial evidence that decreased sunlight exposure and diminished vitamin D nutritional status may be related to an increased risk of cancer.
allows dysregulation seen in adaptive immune responses in T1D, rheumatoid arthritis, multiple sclerosis, Chron’s, ulcerative colitis, and lupus.
precedes neurodegenerative disease as seen in Alzheimer’s, Parkinson’s, etc
associated with cardiovascular disease conditions such as high blood pressure, Vascular endothelium dysfunction, atherosclerosis, coronary heart disease, ischemic heart disease, coronary artery disease, heart failure, stroke, and myocardial infarction
increase in acute upper respiratory infections and increased risk of COVID-19 infection
increased prevalence of atopic dermatitis associated with eczema, skin infections, food allergies, asthma, and allergic rhinitis.
this is just a small list of the vitamin d deficient disease processes perpetuated and not considered an all inclusive list.
Dosing:
to convert from IUs to mcg or mg, or the other direction, see this link.
For Vitamin D: IUs divided by 40 gives mcg dose. Mcg’s multiplied by 40 gives IUs.
FDA recommended: originally 400 IUs (10 mcg) per day, now 600 IUs (15 mcg) per day
Actual nutritional dose: 1,000 IUs (25 mcg) - 5,000 IUs (125 mcg)
Daily therapeutic doses: 5,000 IUs (125 mcg) - 10,000 IUs (250 mcg)
Toxicity:
toxicity induces abnormally high serum calcium concentration (hypercalcemia), which could result in bone loss, kidney stones, constipation, high blood pressure, gallbladder dysfunction, liver dysfunction, and calcification of organs like the heart and kidneys if untreated over a long period of time.
hypercalcemia has been observed following daily doses of greater than 50,000 IU of vitamin D.
Early symptoms of hypercalcemia, include nausea and vomiting, weakness, headache, somnolence, dry mouth, constipation, metallic taste, muscle pain and bone pain.
Late symptoms and signs of hypercalcemia, include frequent urination, extreme thirst, no desire to eat, weight loss, bed wetting or excessive night time urination, red eyes, pancreatitis, light sensitivity, runny nose, extreme itchiness, increased body heat and intolerance to heat, decreased libido, elevated BUN, albuminuria, hypercholesterolemia, elevated ALT (SGPT) and AST (SGOT), calcification of soft tissue structures, calcium deposits in the kidney, high blood pressure and cardiac arrhythmias.
Vitamin E
Names: alpha-, beta-, gamma-, delta- tocopherols, and alpha-, beta-, gamma-, delta- tocotrienols. Research is largely surrounding alpha-tocopherol but there are biological uses of the rest that aren’t well researched. However, if nature contains all 8, then you know that is for a reason as they all work synergistically together as intended (Created).
Essential: meaning you must consume it from your diet.
Sources:
almonds (and oils)
hazlenuts (and oils)
pistachios (and oils)
avocados (and oils)
green olives (and oils)
wild caught algae/green plant eating fish
all peppers (and seeds, and seed oils)
pecans (and oils)
coconut (and oils)
kiwi and apricots (and seeds, and seed oils)
pumpkin (and seeds, and seed oils)
cinnamon, poppy seed, caraway seed, mustard seed, cumin seed, and turmeric
Functions:
chain-breaking potent antioxidant
prevents the propagation of free radicals in membranes and plasma lipoproteins like LDL by becoming oxidized themselves
maintains the integrity of cell membranes throughout the body
vitamin C can regenerate vitamin E’s antioxidant capacity
reduces cardiovascular disease
tocotrienols and gamma-tocopherol are thought to be better scavengers of peroxyl radicals and reactive nitrogen species, respectively, than alpha-tocopherol
tocotrienols might be beneficial in the prevention of chronic diseases
tocotrienols (especially delta-tocotrienol) have shown greater anti-proliferative and pro-apoptotic effects than tocopherols in malignant cancer cell lines
alpha-Tocopherol has been shown to enhance specifically the T cell-mediated immune response that declines with advancing age
possess anticancer activity by protecting cells and DNA against oxidative damage.
Neuroprotectant, protects the CNS and the peripheral nervous system from disease process and oxidative stress
anti-coagulant : a metabolite of vitamin E called vitamin E quinone or alpha-tocopheryl quinone (TQ) is a potent anticoagulant. This metabolite inhibits vitamin K-dependent carboxylase, which is a major enzyme in the coagulation cascade.
Deficient disease processes: seen in poor diets and in malabsorption GI tract and liver/gallbladder diseases.
peripheral neuropathy (nerve disease and sensory/motor dysfunction)
ataxia (movement issues)
skeletal myopathy (disease of the musculoskeletal system)
retinopathy (disease of the retina)
suppression of the immune response
DNA damage
increased oxidative stress and cellular membrane damage to all cells and tissues
neurodegenerative disease processes through increased oxidation
Dosing: to convert from IUs to mcg or mg, or the other direction, see this link.
The synthetic form of vitamin E is the “dl-alpha tocopherol” form. If you see this form, you just multiply the IU by 0.45 to get mg, and to change the mg to IUs you divide the mg by 0.45. You should avoid taking the synthetic forms of vitamin E. If it has a “d” followed by an “l” before “alpha, gamma, beta, delta tocopherol” it is the synthetic form.
Naturally-sourced vitamin E is called “d-alpha, d-gamma, d-beta, d-delta tocopherol and tocotrienol.” If you see “d by itself, without the l, before alpha, gamma, beta, delta tocopherol/tocotrienol” on the label, it’s the natural source, therefore just multiply the IU by 0.67 to get mg, and divide the mg by 0.67 to get IUs.
Of note, mg-to-IU conversion factors are such that the UL in IU for synthetic tocopherol (all-rac-α-tocopherol) is 1.10 times the UL in mg, and the UL in IU for natural tocopherol (RRR-α-tocopherol) is 1.50 times the UL in mg
FDA recommended: originally 30 IUs (20.1 mg), but reduced to 22 IUs (15 mg)
Actual nutritional dose: 75 IUs (50 mg) - 750 IUs (500 mg) per day
Daily therapeutic doses: 750 IUs (500 mg) - 1500 IUs (1,000 mg) per day
Toxicity: above 1500 IUs (1,000 mg) per day for 3 months resulted in minor symptoms. No other long term or high dose studies above 1500 IUs per day have been performed.
Vitamin K
Names:
phylloquinone (vitamin K1)
menaquinones (vitamin K2)
MK-4, MK-7, MK-9, MK-13
Essential: meaning you must consume these from your diet. The lack of internal storage of vitamin K contributes to rapid depletion, therefore adequate dietary intake is necessary.
Sources:
phylloquinone (vitamin K1)-is synthesized by plants
menaquinones (vitamin K2)-synthesized by human intestinal microbiota (gut flora), and found in fermented foods and in animal products— like grass-fed dairy fat products (milk, butter, and cheese) and grass-fed liver.
Functions: with limited vitamin K storage capacity, the body recycles vitamin K in the vitamin K oxidation-reduction cycle in order to reuse it multiple times.
blood coagulation- abnormal clotting is not related to excessive vitamin K intake, and there is no known toxicity associated with vitamin K1 or vitamin K2
assist in increasing bone mass density
prevention of vessel calcification and cardiovascular events due to vessel hardening and narrowing.
growth arrest-specific gene 6 protein (Gas6) is a vitamin K-dependent protein found throughout the nervous system, as well in the heart, lungs, stomach, kidneys, and cartilage.
Deficient disease processes- seen with inadequate dietary intake, but mostly with fat malabsorption diseases (cystic fibrosis, Crohn's disease, ulcerative colitis, Whipple's disease, celiac sprue, short bowel syndrome) and loss of storage sites due to liver disease and primary biliary cirrhosis.
increase the risk of osteoporosis and fractures.
severe liver disease results in lower blood levels of vitamin K-dependent clotting factors and an increased risk for uncontrolled bleeding—hemorrhage
easy bruising and bleeding that may be manifested as nosebleeds, bleeding gums, blood in the urine, blood in the stool, tarry black stools, or extremely heavy menstrual bleeding
abnormal artery and vein (vessel) calcification
Dosing
FDA recommended: originally 80 mcg and has since increased to 120 mcg
Actual nutritional dose: 100 mcg - 300 mcg per day
Daily therapeutic doses: 300 mcg per day
Toxicity: there is no known toxicity associated with vitamin K1 or vitamin K2
This concludes the Quality Parts and Tools section on “vitamins”. As you can see, each of these vitamins perform essential functions in the human body that are necessary not only for health but deficiencies will result in progressive disease states and eventually lead to (early) death. What you put into your body is just as significant as the quality of it.
Billions upon billions of simultaneous chemical reactions are occurring inside you at this very moment, and how fast they are able to perform them is dictated by the amount of materials/supplies and parts/tools you have available—in many cases you simply can’t create matter out of nothing and these nutrients are “essential” meaning you MUST consume them.
Your body is a Ferrari.
-Are you putting anything but premium unleaded in the gas tank?
-Diesel is great fuel, but are you putting it in?
All things are lawful, yes.
But not all things are profitable.
Eat to live.
Don’t live to eat.
Think about and choose carefully what you put in your body. It may cost you more up front to eat healthier, but you are going to pay for it one way or another inevitably (the hospital, western medicine, and Big Pharma await your future arrival should you choose poorly now).
Quality Parts and Tools: Part 3 will include the equally essential minerals necessary to maintain hydration and contribute as well to the rest of the chemical reactions in the body.
With your CNS turned on and an adequate amount of quality materials and supplies, and a full compliment of quality parts and tools, your body will live, thrive, and heal from most dis-ease and disease processes.
Once we have covered those, we will discuss specific GI dysbiosis, GI disease, and nutrient deficient dis-ease processes, water and salt for proper hydration, and restoring proper pH balancing to run your system efficiently.
For all paid subscribers, I will post all of my protocols, where specific diets and micronutrient protocols are used therapeutically (instead of nutritionally) in order to fast track the healing process, as well as allow you to contact me, fill out special intake forms, and get access to directly shipped, quality supplementation that is 3rd party tested, clean, contaminant free, and highly bioavailable (easily absorbed).
In subsequent articles, we will cover adaptive/autoimmune dis-eases, detoxing heavy metals, halogens, and clearing infectious processes including dysbiosis, LIBO, SIBO, fungal, yeast, candida, viral infections, altered cellular DNA, and more.
After that we will put all the protocols together to give you the 40,000 ft view and simplify all of it to show you just how easy it is to regenerate, heal, and maintain your health and function.
At the end of it all, we will cover functional movement, muscle building, fast tracking tissue injury regeneration, electromagnetism, light and frequency therapeutics, and how to accomplish all of these things, whether by yourself or who to go see locally and what to ask for to get these issues resolved and improve the quality of your life—stuff you won’t find in one spot elsewhere and stuff the mainstream healthcare systems do not want you to know because it interferes with their bottom line.
You will NOT be disappointed.
If you expect to be able to keep your health into your late years, and you totally can, then following this pathway will allow you to do so.
Stay tuned!!! You WON’T want to miss this!!!!
This article includes some of its hyperlinks to a website provided by the Linus Pauling Institute at Oregon State University. “Dr. C’s Health and Wellness” is not affiliated or endorsed by the Linus Pauling Institute or Oregon State University.
Hello Dr C, I am interested in the master reset. I emailed you my info about 10 days ago but haven’t gotten a reply yet. Can you give me an idea about how long it might take to hear back from you? Thank you very much Amy W.
Hello I think I found you! I was speaking with you on TruthSocial I have Hashimoto's and serious inflammation issues and adenoma on my pituitary gland that's messing with my whole IGF growth factor insulin resistant type stuff and I have Hashimoto's as I said but my hyper inflammation is unreal after I had Covid three times I am not Vaxxed I've been dealing with so much for 30 years I hope this gets to you I pray that it gets to you you said that you would help me guiding me through and perhaps giving me the supplements wholesale I thank you so much Crazy McNally or Angie Harmon